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Mechanisms of palmitate-induced cell death in human osteoblasts

Lipotoxicity is an overload of lipids in non-adipose tissues that affects function and induces cell death. Lipotoxicity has been demonstrated in bone cells in vitro using osteoblasts and adipocytes in coculture. In this condition, lipotoxicity was induced by high levels of saturated fatty acids (mos...

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Detalles Bibliográficos
Autores principales: Gunaratnam, Krishanthi, Vidal, Christopher, Boadle, Ross, Thekkedam, Chris, Duque, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863423/
https://www.ncbi.nlm.nih.gov/pubmed/24285710
http://dx.doi.org/10.1242/bio.20136700