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Mechanisms of palmitate-induced cell death in human osteoblasts
Lipotoxicity is an overload of lipids in non-adipose tissues that affects function and induces cell death. Lipotoxicity has been demonstrated in bone cells in vitro using osteoblasts and adipocytes in coculture. In this condition, lipotoxicity was induced by high levels of saturated fatty acids (mos...
Autores principales: | Gunaratnam, Krishanthi, Vidal, Christopher, Boadle, Ross, Thekkedam, Chris, Duque, Gustavo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863423/ https://www.ncbi.nlm.nih.gov/pubmed/24285710 http://dx.doi.org/10.1242/bio.20136700 |
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