The snRNA-processing complex, Integrator, is required for ciliogenesis and dynein recruitment to the nuclear envelope via distinct mechanisms

We previously reported that the small nuclear RNA processing complex, Integrator, is required for dynein recruitment to the nuclear envelope at mitotic onset in cultured human cells. We now report an additional role for INT in ciliogenesis. Depletion of INT subunits from cultured human cells results...

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Detalles Bibliográficos
Autores principales: Jodoin, Jeanne N., Shboul, Mohammad, Albrecht, Todd R., Lee, Ethan, Wagner, Eric J., Reversade, Bruno, Lee, Laura A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863424/
https://www.ncbi.nlm.nih.gov/pubmed/24285713
http://dx.doi.org/10.1242/bio.20136981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863424/
https://www.ncbi.nlm.nih.gov/pubmed/24285713
http://dx.doi.org/10.1242/bio.20136981

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