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Synthesis of Two Novel 3-Amino-5-[4-chloro-2-phenoxyphenyl]-4H-1,2,4-triazoles with Anticonvulsant Activity

Two novel 3-amino-5-(4-choloro-2-phenoxyphenyl)-4H-1,2,4-triazole derivatives were prepared and their anticonvulsant activity was measured by evaluation of the ability of these compounds to protect mice against convulsion induced by lethal doses of pentylenetetrazole (PTZ). Diazepam (Sigma) was cons...

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Detalles Bibliográficos
Autores principales: Mahdavi, Mohammad, Akbarzadeh, Tahmineh, Sheibani, Vahid, Abbasi, Maryam, Firoozpour, Loghman, Tabatabai, Sayyed Abbas, Shafiee, Abbas, Foroumadi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863441/
https://www.ncbi.nlm.nih.gov/pubmed/24363736