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Cholesterol Contributes to Diabetic Nephropathy through SCAP-SREBP-2 Pathway

Diabetic nephropathy (DN) has been associated with the presence of lipid deposition. We hypothesized that the disruption of intracellular cholesterol feedback may contribute to DN. Diabetes was induced by high fat/sucrose diet and low-dose intraperitoneal injection of streptozocin (STZ) in male Spra...

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Detalles Bibliográficos
Autores principales: Sun, Hong, Yuan, Yang, Sun, Zi-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863482/
https://www.ncbi.nlm.nih.gov/pubmed/24369464
http://dx.doi.org/10.1155/2013/592576