A Novel Bone Morphogenetic Protein 2 Mutant Mouse, nBmp2NLS(tm), Displays Impaired Intracellular Ca(2+) Handling in Skeletal Muscle

We recently reported a novel form of BMP2, designated nBMP2, which is translated from an alternative downstream start codon and is localized to the nucleus rather than secreted from the cell. To examine the function of nBMP2 in the nucleus, we engineered a gene-targeted mutant mouse model (nBmp2NLS(...

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Detalles Bibliográficos
Autores principales: Bridgewater, Laura C., Mayo, Jaime L., Evanson, Bradley G., Whitt, Megan E., Dean, Spencer A., Yates, Joshua D., Holden, Devin N., Schmidt, Alina D., Fox, Christopher L., Dhunghel, Saroj, Steed, Kevin S., Adam, Michael M., Nichols, Caitlin A., Loganathan, Sampath K., Barrow, Jeffery R., Hancock, Chad R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863484/
https://www.ncbi.nlm.nih.gov/pubmed/24369527
http://dx.doi.org/10.1155/2013/125492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863484/
https://www.ncbi.nlm.nih.gov/pubmed/24369527
http://dx.doi.org/10.1155/2013/125492

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