Cargando…

A Novel Bone Morphogenetic Protein 2 Mutant Mouse, nBmp2NLS(tm), Displays Impaired Intracellular Ca(2+) Handling in Skeletal Muscle

We recently reported a novel form of BMP2, designated nBMP2, which is translated from an alternative downstream start codon and is localized to the nucleus rather than secreted from the cell. To examine the function of nBMP2 in the nucleus, we engineered a gene-targeted mutant mouse model (nBmp2NLS(...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bridgewater, Laura C., Mayo, Jaime L., Evanson, Bradley G., Whitt, Megan E., Dean, Spencer A., Yates, Joshua D., Holden, Devin N., Schmidt, Alina D., Fox, Christopher L., Dhunghel, Saroj, Steed, Kevin S., Adam, Michael M., Nichols, Caitlin A., Loganathan, Sampath K., Barrow, Jeffery R., Hancock, Chad R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863484/ https://www.ncbi.nlm.nih.gov/pubmed/24369527 http://dx.doi.org/10.1155/2013/125492

Ejemplares similares

The nuclear variant of bone morphogenetic protein 2 (nBMP2) is expressed in macrophages and alters calcium response
por: Tellez Freitas, Claudia M., et al.
Publicado: (2019)

The BMP2 nuclear variant, nBMP2, is expressed in mouse hippocampus and impacts memory
por: Cordner, Ryan D., et al.
Publicado: (2017)

Expression of genes for bone morphogenetic proteins BMP-2, BMP-4 and BMP-6 in various parts of the human skeleton
por: Kochanowska, Iwona, et al.
Publicado: (2007)

Sustained delivery of the bone morphogenetic proteins BMP-2 and BMP-7 for cartilage repair and regeneration in osteoarthritis
por: Whitty, Ciara, et al.
Publicado: (2022)

Semiclassical focussing NLS
por: Kamvissis, S
Publicado: (2003)

Stimulation of Bone Healing by Sustained Bone Morphogenetic Protein 2 (BMP-2) Delivery
por: Faßbender, Mirja, et al.
Publicado: (2014)

Bone Morphogenetic Protein 2 (BMP-2) Aggregates Can be Solubilized by Albumin—Investigation of BMP-2 Aggregation by Light Scattering and Electrophoresis
por: Sundermann, Julius, et al.
Publicado: (2020)

The use of recombinant human bone morphogenetic protein-2 (rhBMP-2) in maxillofacial trauma
por: Herford, A.S.
Publicado: (2017)

Semiclassical NLS on the half line
por: Kamvissis, S
Publicado: (2002)

Osteoinduction by combining bone morphogenetic protein (BMP)-2 with a bioactive novel nanocomposite
por: Sharma, A., et al.
Publicado: (2012)

Functional exchangeability of the nuclear localization signal (NLS) of capsid protein between PCV1 and PCV2 in vitro: Implications for the role of NLS in viral replication
por: Shuai, Jiangbing, et al.
Publicado: (2011)

Safety and Efficacy of Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) in Craniofacial Surgery
por: Ramly, Elie P., et al.
Publicado: (2019)

Simultaneous gene transfer of bone morphogenetic protein (BMP) -2 and BMP-7 by in vivo electroporation induces rapid bone formation and BMP-4 expression
por: Kawai, Mariko, et al.
Publicado: (2006)

Retraction: Self-association of L-periaxin occurs via its acidic domain and NLS2/NLS3, and affects its trafficking in RSC96 cells
por: Yang, Yenan, et al.
Publicado: (2021)

Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2
por: Lyst, Matthew J., et al.
Publicado: (2018)

Human bone morphogenetic protein-2 (hBMP-2) characterization by physical–chemical, immunological and biological assays
por: Suzuki, Miriam Fussae, et al.
Publicado: (2020)

On the question of analyticity of data for semiclassical NLS
por: Kamvissis, S
Publicado: (2001)

On the question of analyticity of data for semiclassical NLS
por: Kamvissis, S
Publicado: (2002)

Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling
por: Davidson, Esmeralda N Blaney, et al.
Publicado: (2007)

Recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) in posterolateral lumbar spine fusion: complications in the elderly
por: Hoffmann, Martin F, et al.
Publicado: (2013)

Bone morphogenetic protein 2 (BMP2) induces growth suppression and enhances chemosensitivity of human colon cancer cells
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2016)

Stimulation of primordial follicle assembly by estradiol-17β requires the action of bone morphogenetic protein-2 (BMP2)
por: Chakraborty, Prabuddha, et al.
Publicado: (2017)

Expression of the Bone Morphogenetic Protein-2 (BMP2) in the Human Cumulus Cells as a Biomarker of Oocytes and Embryo Quality
por: Demiray, Sirin B., et al.
Publicado: (2017)

A Comparative Genomic and Transcriptional Survey Providing Novel Insights into Bone Morphogenetic Protein 2 (bmp2) in Fishes
por: Yang, Guang, et al.
Publicado: (2019)

Current Trends in Recombinant Human Bone Morphogenetic Protein 2 (rhBMP2) Usage for Spinal Fusion Surgery
por: Patel, Harshadkumar A., et al.
Publicado: (2023)

Current Status of Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) in Maxillofacial Surgery: Should It Be Continued?
por: On, Sung-Woon, et al.
Publicado: (2023)

Nuclear variants of bone morphogenetic proteins
por: Felin, Jenny E, et al.
Publicado: (2010)

Dissecting the roles of Cse1 and Nup2 in classical NLS‐cargo release in vivo
por: Lange, Allison, et al.
Publicado: (2020)

Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis
por: Core, Amanda B., et al.
Publicado: (2014)

Bone Morphogenetic Protein (BMP) signaling in development and human diseases
por: Wang, Richard N., et al.
Publicado: (2014)

Upregulation of bone morphogenetic protein 2 (Bmp2) in dorsal root ganglion in a rat model of bone cancer pain
por: Wang, Wei, et al.
Publicado: (2019)

Postulated release profile of recombinant human bone morphogenetic protein-2 (rhBMP-2) from demineralized dentin matrix
por: Um, In-Woong, et al.
Publicado: (2019)

Human salivary histatin‐1 (Hst1) promotes bone morphogenetic protein 2 (BMP2)‐induced osteogenesis and angiogenesis
por: Sun, Ping, et al.
Publicado: (2020)

RNA sequence analysis identified bone morphogenetic protein-2 (BMP2) as a biomarker underlying form deprivation myopia
por: Chen, Chun-Wen, et al.
Publicado: (2022)

Efficient delivery of recombinant human bone morphogenetic protein (rhBMP-2) with dextran sulfate-chitosan microspheres
por: Xia, Yuan-Jun, et al.
Publicado: (2018)

Two novel mutations in exon 2 of bone morphogenetic protein (BMP) 15 gene in Pakistani infertile females
por: Faiza, Hafiza, et al.
Publicado: (2021)

Participation of Selected Soluble BMP-2 and BMP-7 Bone Morphogenetic Proteins and Their Soluble Type I ALK-1 and Type II BMPR2 Receptors in Formation and Development of Endometriosis
por: Janusz, Joanna, et al.
Publicado: (2021)

Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) for the Treatment of Nonunion of the Femur in Children and Adolescents: A Retrospective Analysis
por: Hissnauer, Tim N., et al.
Publicado: (2017)

A Novel Long Noncoding RNA, Lnc-OAD, Is Required for Bone Morphogenetic Protein 2- (BMP-2-) Induced Osteoblast Differentiation
por: Wang, Zonggui, et al.
Publicado: (2021)

Human Fresh Fibrin Membrane with Bone Morphogenetic Protein-2 (BMP-2) Induces Bone Formation in the Subcutaneous Tissues of Nude Mice
por: Onji, Keiko, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fqq2cigpoh20q38ljvfuimjb4j