Synaptic Dysfunction in Prion Diseases: A Trafficking Problem?

Synaptic dysfunction is an important cause of neurological symptoms in prion diseases, a class of clinically heterogeneous neurodegenerative disorders caused by misfolding of the cellular prion protein (PrP(C)). Experimental data suggest that accumulation of misfolded PrP(C) in the endoplasmic retic...

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Detalles Bibliográficos
Autores principales: Senatore, Assunta, Restelli, Elena, Chiesa, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863542/
https://www.ncbi.nlm.nih.gov/pubmed/24369467
http://dx.doi.org/10.1155/2013/543803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863542/
https://www.ncbi.nlm.nih.gov/pubmed/24369467
http://dx.doi.org/10.1155/2013/543803

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