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An emerging role for misfolded wild-type SOD1 in sporadic ALS pathogenesis
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder that targets motor neurons, leading to paralysis and death within a few years of disease onset. While several genes have been linked to the inheritable, or familial, form of ALS, much less is known about the cause(s) of sporad...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863749/ https://www.ncbi.nlm.nih.gov/pubmed/24379756 http://dx.doi.org/10.3389/fncel.2013.00253 |