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An emerging role for misfolded wild-type SOD1 in sporadic ALS pathogenesis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder that targets motor neurons, leading to paralysis and death within a few years of disease onset. While several genes have been linked to the inheritable, or familial, form of ALS, much less is known about the cause(s) of sporad...

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Detalles Bibliográficos
Autores principales: Rotunno, Melissa S., Bosco, Daryl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863749/
https://www.ncbi.nlm.nih.gov/pubmed/24379756
http://dx.doi.org/10.3389/fncel.2013.00253

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