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On multi-marker tests for association in case-control studies

Genome-wide association studies (GWAs) have identified thousands of DNA loci associated with a variety of traits. Statistical inference is almost always based on single marker hypothesis tests of association and the respective p-values with Bonferroni correction. Since commercially available genomic...

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Detalles Bibliográficos
Autores principales: Taub, Margaret A., Schwender, Holger R., Younkin, Samuel G., Louis, Thomas A., Ruczinski, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863805/
https://www.ncbi.nlm.nih.gov/pubmed/24379823
http://dx.doi.org/10.3389/fgene.2013.00252