Epalrestat increases intracellular glutathione levels in Schwann cells through transcription regulation()

Epalrestat (EPS), approved in Japan, is the only aldose reductase inhibitor that is currently available for the treatment of diabetic neuropathy. Here we report that EPS at near-plasma concentration increases the intracellular levels of glutathione (GSH), which is important for protection against ox...

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Detalles Bibliográficos
Autores principales: Sato, Keisuke, Yama, Kaori, Murao, Yu, Tatsunami, Ryosuke, Tampo, Yoshiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863807/
https://www.ncbi.nlm.nih.gov/pubmed/24363998
http://dx.doi.org/10.1016/j.redox.2013.11.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863807/
https://www.ncbi.nlm.nih.gov/pubmed/24363998
http://dx.doi.org/10.1016/j.redox.2013.11.003

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