Integrated enzyme reactor and high resolving chromatography in “sub-chip” dimensions for sensitive protein mass spectrometry

Reliable, sensitive and automatable analytical methodology is of great value in e.g. cancer diagnostics. In this context, an on-line system for enzymatic cleavage of proteins, subsequent peptide separation by liquid chromatography (LC) with mass spectrometric detection has been developed using “sub-...

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Detalles Bibliográficos
Autores principales: Hustoft, Hanne Kolsrud, Brandtzaeg, Ole Kristian, Rogeberg, Magnus, Misaghian, Dorna, Torsetnes, Silje Bøen, Greibrokk, Tyge, Reubsaet, Léon, Wilson, Steven Ray, Lundanes, Elsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863811/
https://www.ncbi.nlm.nih.gov/pubmed/24336509
http://dx.doi.org/10.1038/srep03511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863811/
https://www.ncbi.nlm.nih.gov/pubmed/24336509
http://dx.doi.org/10.1038/srep03511

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