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Dual-Targeting Pro-apoptotic Peptide for Programmed Cancer Cell Death via Specific Mitochondria Damage

Mitochondria are vital organelles to eukaryotic cells. Damage to mitochondria will cause irreversible cell death or apoptosis. In this report, we aim at programmed cancer cell death via specific mitochondrial damage. Herein, a functionalized pro-apoptotic peptide demonstrates a dual-targeting capabi...

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Detalles Bibliográficos
Autores principales: Chen, Wei-Hai, Xu, Xiao-Ding, Luo, Guo-Feng, Jia, Hui-Zhen, Lei, Qi, Cheng, Si-Xue, Zhuo, Ren-Xi, Zhang, Xian-Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863817/
https://www.ncbi.nlm.nih.gov/pubmed/24336626
http://dx.doi.org/10.1038/srep03468