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Mechanisms of leading edge protrusion in interstitial migration

While the molecular and biophysical mechanisms underlying cell protrusion on two-dimensional substrates are well understood, our knowledge of the actin structures driving protrusion in three-dimensional environments is poor, despite relevance to inflammation, development and cancer. Here we report t...

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Detalles Bibliográficos
Autores principales: Wilson, Kerry, Lewalle, Alexandre, Fritzsche, Marco, Thorogate, Richard, Duke, Tom, Charras, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863902/
https://www.ncbi.nlm.nih.gov/pubmed/24305616
http://dx.doi.org/10.1038/ncomms3896