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Mechanisms of molecular transport through the urea channel of Helicobacter pylori

Helicobacter pylori survival in acidic environments relies on cytoplasmic hydrolysis of gastric urea into ammonia and carbon dioxide, which buffer the pathogen’s periplasm. Urea uptake is greatly enhanced and regulated by HpUreI, a proton-gated inner membrane channel protein essential for gastric su...

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Detalles Bibliográficos
Autores principales: McNulty, Reginald, Ulmschneider, Jakob P., Luecke, Hartmut, Ulmschneider, Martin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863980/
https://www.ncbi.nlm.nih.gov/pubmed/24305683
http://dx.doi.org/10.1038/ncomms3900