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Interactions of Tenofovir, Lamivudine, Abacavir and Didanosine in Primary Human Cells

Certain triple nucleoside/tide reverse transcriptase inhibitor (NRTI) regimens containing tenofovir (TDF) have been associated with rapid early treatment failure. The mechanism is unknown, but may be at the level of drug transport. We measured the lipophilicity of the drugs [(3)H]-lamivudine (3TC),...

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Detalles Bibliográficos
Autores principales: Janneh, Omar, Khoo, Saye H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864238/
https://www.ncbi.nlm.nih.gov/pubmed/24310499
http://dx.doi.org/10.3390/pharmaceutics3020326