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Importance of Toxin A, Toxin B, and CDT in Virulence of an Epidemic Clostridium difficile Strain

Clostridium difficile infection is the main cause of healthcare-acquired diarrhea in the developed world. In addition to the main virulence factors toxin A and B, epidemic, PCR Ribotype 027 strains, such as R20291, produce a third toxin, CDT. To develop effective medical countermeasures, it is impor...

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Detalles Bibliográficos
Autores principales: Kuehne, Sarah A., Collery, Mark M., Kelly, Michelle L., Cartman, Stephen T., Cockayne, Alan, Minton, Nigel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864386/
https://www.ncbi.nlm.nih.gov/pubmed/23935202
http://dx.doi.org/10.1093/infdis/jit426