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MicroRNA-146a Represses Mycobacteria-Induced Inflammatory Response and Facilitates Bacterial Replication via Targeting IRAK-1 and TRAF-6

BACKGROUND: Apart from triggering host immune responses, macrophages also act as a major reservoir for mycobacteria. For better survival, mycobacteria have evolved various mechanisms to modulate the production of proinflammatory cytokines in macrophages, and manipulation of micro-RNA (miRNA) express...

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Detalles Bibliográficos
Autores principales: Li, Shuo, Yue, Yan, Xu, Wei, Xiong, Sidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864784/
https://www.ncbi.nlm.nih.gov/pubmed/24358114
http://dx.doi.org/10.1371/journal.pone.0081438