Interferon-β Induced microRNA-129-5p Down-Regulates HPV-18 E6 and E7 Viral Gene Expression by Targeting SP1 in Cervical Cancer Cells

Infection by human papillomavirus (HPV) can cause cervical intraepithelial neoplasia (CIN) and cancer. Down-regulation of E6 and E7 expression may be responsible for the positive clinical outcomes observed with IFN treatment, but the molecular basis has not been well determined. As miRNAs play an im...

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Detalles Bibliográficos
Autores principales: Zhang, Jiarong, Li, Shuangdi, Yan, Qin, Chen, Xiaoyue, Yang, Yixia, Liu, Xuelian, Wan, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864787/
https://www.ncbi.nlm.nih.gov/pubmed/24358111
http://dx.doi.org/10.1371/journal.pone.0081366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864787/
https://www.ncbi.nlm.nih.gov/pubmed/24358111
http://dx.doi.org/10.1371/journal.pone.0081366

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