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Interferon-β Induced microRNA-129-5p Down-Regulates HPV-18 E6 and E7 Viral Gene Expression by Targeting SP1 in Cervical Cancer Cells
Infection by human papillomavirus (HPV) can cause cervical intraepithelial neoplasia (CIN) and cancer. Down-regulation of E6 and E7 expression may be responsible for the positive clinical outcomes observed with IFN treatment, but the molecular basis has not been well determined. As miRNAs play an im...
Autores principales: | Zhang, Jiarong, Li, Shuangdi, Yan, Qin, Chen, Xiaoyue, Yang, Yixia, Liu, Xuelian, Wan, Xiaoping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864787/ https://www.ncbi.nlm.nih.gov/pubmed/24358111 http://dx.doi.org/10.1371/journal.pone.0081366 |
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