Development and Application of Genomic Control Methods for Genome-Wide Association Studies Using Non-Additive Models

Genome-wide association studies (GWAS) comprise a powerful tool for mapping genes of complex traits. However, an inflation of the test statistic can occur because of population substructure or cryptic relatedness, which could cause spurious associations. If information on a large number of genetic m...

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Detalles Bibliográficos
Autores principales: Tsepilov, Yakov A., Ried, Janina S., Strauch, Konstantin, Grallert, Harald, van Duijn, Cornelia M., Axenovich, Tatiana I., Aulchenko, Yurii S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864791/
https://www.ncbi.nlm.nih.gov/pubmed/24358113
http://dx.doi.org/10.1371/journal.pone.0081431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864791/
https://www.ncbi.nlm.nih.gov/pubmed/24358113
http://dx.doi.org/10.1371/journal.pone.0081431

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