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Development and Application of Genomic Control Methods for Genome-Wide Association Studies Using Non-Additive Models
Genome-wide association studies (GWAS) comprise a powerful tool for mapping genes of complex traits. However, an inflation of the test statistic can occur because of population substructure or cryptic relatedness, which could cause spurious associations. If information on a large number of genetic m...
Autores principales: | Tsepilov, Yakov A., Ried, Janina S., Strauch, Konstantin, Grallert, Harald, van Duijn, Cornelia M., Axenovich, Tatiana I., Aulchenko, Yurii S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864791/ https://www.ncbi.nlm.nih.gov/pubmed/24358113 http://dx.doi.org/10.1371/journal.pone.0081431 |
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