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Rab GTPase Prenylation Hierarchy and Its Potential Role in Choroideremia Disease
Protein prenylation is a widespread post-translational modification in eukaryotes that plays a crucial role in membrane targeting and signal transduction. RabGTPases is the largest group of post-translationally C-terminally geranylgeranylated. All Rabs are processed by Rab geranylgeranyl-transferase...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864799/ https://www.ncbi.nlm.nih.gov/pubmed/24358126 http://dx.doi.org/10.1371/journal.pone.0081758 |