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Rab GTPase Prenylation Hierarchy and Its Potential Role in Choroideremia Disease

Protein prenylation is a widespread post-translational modification in eukaryotes that plays a crucial role in membrane targeting and signal transduction. RabGTPases is the largest group of post-translationally C-terminally geranylgeranylated. All Rabs are processed by Rab geranylgeranyl-transferase...

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Detalles Bibliográficos
Autores principales: Köhnke, Monika, Delon, Christine, Hastie, Marcus L., Nguyen, Uyen T. T., Wu, Yao-Wen, Waldmann, Herbert, Goody, Roger S., Gorman, Jeffrey J., Alexandrov, Kirill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864799/
https://www.ncbi.nlm.nih.gov/pubmed/24358126
http://dx.doi.org/10.1371/journal.pone.0081758