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Mechanism of farnesylated CAAX protein processing by the integral membrane protease Rce1

CAAX proteins play essential roles in multiple signalling pathways, controlling processes such as proliferation, differentiation and carcinogenesis (1). The ~120 mammalian CAAX proteins function at cellular membranes and include the Ras superfamily of small GTPases, nuclear lamins, the γ-subunit of...

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Detalles Bibliográficos
Autores principales: Manolaridis, Ioannis, Kulkarni, Kiran, Dodd, Roger B., Ogasawara, Satoshi, Zhang, Ziguo, Bineva, Ganka, Reilly, Nicola O’, Hanrahan, Sarah J., Thompson, Andrew J., Cronin, Nora, Iwata, So, Barford, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864837/
https://www.ncbi.nlm.nih.gov/pubmed/24291792
http://dx.doi.org/10.1038/nature12754