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Identification of Navβ1 Residues Involved in the Modulation of the Sodium Channel Nav1.4

Voltage-gated sodium channels (VGSCs) are heteromeric protein complexes that initiate action potentials in excitable cells. The voltage-gated sodium channel accessory subunit, Navβ1, allosterically modulates the α subunit pore structure upon binding. To date, the molecular determinants of the interf...

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Detalles Bibliográficos
Autores principales: Islas, Angel A., Sánchez-Solano, Alfredo, Scior, Thomas, Millan-PerezPeña, Lourdes, Salinas-Stefanon, Eduardo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864903/
https://www.ncbi.nlm.nih.gov/pubmed/24358138
http://dx.doi.org/10.1371/journal.pone.0081995