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Identification of Navβ1 Residues Involved in the Modulation of the Sodium Channel Nav1.4
Voltage-gated sodium channels (VGSCs) are heteromeric protein complexes that initiate action potentials in excitable cells. The voltage-gated sodium channel accessory subunit, Navβ1, allosterically modulates the α subunit pore structure upon binding. To date, the molecular determinants of the interf...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864903/ https://www.ncbi.nlm.nih.gov/pubmed/24358138 http://dx.doi.org/10.1371/journal.pone.0081995 |