Identification of Crucial Amino Acids in Mouse Aldehyde Oxidase 3 That Determine Substrate Specificity

In order to elucidate factors that determine substrate specificity and activity of mammalian molybdo-flavoproteins we performed site directed mutagenesis of mouse aldehyde oxidase 3 (mAOX3). The sequence alignment of different aldehyde oxidase (AOX) isoforms identified variations in the active site...

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Detalles Bibliográficos
Autores principales: Mahro, Martin, Brás, Natércia F., Cerqueira, Nuno M. F. S. A., Teutloff, Christian, Coelho, Catarina, Romão, Maria João, Leimkühler, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864932/
https://www.ncbi.nlm.nih.gov/pubmed/24358164
http://dx.doi.org/10.1371/journal.pone.0082285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864932/
https://www.ncbi.nlm.nih.gov/pubmed/24358164
http://dx.doi.org/10.1371/journal.pone.0082285

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