Recruitment into stress granules prevents irreversible aggregation of FUS protein mislocalized to the cytoplasm

Fused in sarcoma (FUS) belongs to the group of RNA-binding proteins implicated as underlying factors in amyotrophic lateral sclerosis (ALS) and certain other neurodegenerative diseases. Multiple FUS gene mutations have been linked to hereditary forms, and aggregation of FUS protein is believed to pl...

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Detalles Bibliográficos
Autores principales: Shelkovnikova, Tatyana A, Robinson, Hannah K, Connor-Robson, Natalie, Buchman, Vladimir L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865015/
https://www.ncbi.nlm.nih.gov/pubmed/24013423
http://dx.doi.org/10.4161/cc.26241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865015/
https://www.ncbi.nlm.nih.gov/pubmed/24013423
http://dx.doi.org/10.4161/cc.26241

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