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Proteasome-dependent degradation of replisome components regulates faithful DNA replication

The replication machinery, or the replisome, collides with a variety of obstacles during the normal process of DNA replication. In addition to damaged template DNA, numerous chromosome regions are considered to be difficult to replicate owing to the presence of DNA secondary structures and DNA-bindi...

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Detalles Bibliográficos
Autores principales: Roseaulin, Laura C, Noguchi, Chiaki, Noguchi, Eishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865046/
https://www.ncbi.nlm.nih.gov/pubmed/23907116
http://dx.doi.org/10.4161/cc.25692