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Proteasome-dependent degradation of replisome components regulates faithful DNA replication
The replication machinery, or the replisome, collides with a variety of obstacles during the normal process of DNA replication. In addition to damaged template DNA, numerous chromosome regions are considered to be difficult to replicate owing to the presence of DNA secondary structures and DNA-bindi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865046/ https://www.ncbi.nlm.nih.gov/pubmed/23907116 http://dx.doi.org/10.4161/cc.25692 |