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Upregulation of Cleavage and Polyadenylation Specific Factor 4 in Lung Adenocarcinoma and Its Critical Role for Cancer Cell Survival and Proliferation

Cleavage and polyadenylation specific factor 4 (CPSF4), a member of CPSF complex, plays a key role in mRNA polyadenylation and mRNA 3′ ends maturation. However, its possible role in lung cancer pathogenesis is unknown. In this study, we investigated the biological role and clinical significance of C...

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Detalles Bibliográficos
Autores principales: Chen, Wangbing, Guo, Wei, Li, Mei, Shi, Dingbo, Tian, Yun, Li, Zhenlin, Wang, Jingshu, Fu, Lingyi, Xiao, Xiangsheng, Liu, Quentin Qiang, Wang, Shusen, Huang, Wenlin, Deng, Wuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865097/
https://www.ncbi.nlm.nih.gov/pubmed/24358221
http://dx.doi.org/10.1371/journal.pone.0082728