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Deficiency of Ataxia Telangiectasia Mutated Kinase Modulates Cardiac Remodeling Following Myocardial Infarction: Involvement in Fibrosis and Apoptosis

Ataxia telangiectasia mutated kinase (ATM) is a cell cycle checkpoint protein activated in response to DNA damage. We recently reported that ATM plays a protective role in myocardial remodeling following β-adrenergic receptor stimulation. Here we investigated the role of ATM in cardiac remodeling us...

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Detalles Bibliográficos
Autores principales: Foster, Cerrone R., Daniel, Laura L., Daniels, Christopher R., Dalal, Suman, Singh, Mahipal, Singh, Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865210/
https://www.ncbi.nlm.nih.gov/pubmed/24358288
http://dx.doi.org/10.1371/journal.pone.0083513