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Two Residues in the Basic Region of the Yeast Transcription Factor Yap8 Are Crucial for Its DNA-Binding Specificity

In Saccharomyces cerevisiae, the transcription factor Yap8 is a key determinant in arsenic stress response. Contrary to Yap1, another basic region-leucine zipper (bZIP) yeast regulator, Yap8 has a very restricted DNA-binding specificity and only orchestrates the expression of ACR2 and ACR3 genes. In...

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Detalles Bibliográficos
Autores principales: Amaral, Catarina, Pimentel, Catarina, Matos, Rute G., Arraiano, Cecília M., Matzapetakis, Manolis, Rodrigues-Pousada, Claudina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865217/
https://www.ncbi.nlm.nih.gov/pubmed/24358276
http://dx.doi.org/10.1371/journal.pone.0083328