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C-Terminal Domain of ICA69 Interacts with PICK1 and Acts on Trafficking of PICK1-PKCα Complex and Cerebellar Plasticity

BACKGROUND: PICK1 (protein interacting with C-kinase 1) is a PKC (protein kinase C)-binding protein, which is essential for synaptic plasticity. The trafficking of PKCα-PICK1 complex to plasma membrane is critical for the internalization of GluR2 and induction of long-term depression. ICA69 (islet c...

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Detalles Bibliográficos
Autores principales: Wang, Zhen, Wang, Ya-Nan, Sun, Cheng-Long, Yang, Dong, Su, Li-Da, Xie, Ya-Jun, Zhou, Lin, Wang, Yin, Shen, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865253/
https://www.ncbi.nlm.nih.gov/pubmed/24358315
http://dx.doi.org/10.1371/journal.pone.0083862