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Characterization of the SigD Regulon of C. difficile and Its Positive Control of Toxin Production through the Regulation of tcdR

Clostridium difficile intestinal disease is mediated largely by the actions of toxins A (TcdA) and B (TcdB), whose production occurs after the initial steps of colonization involving different surface or flagellar proteins. In B. subtilis, the sigma factor SigD controls flagellar synthesis, motility...

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Detalles Bibliográficos
Autores principales: El Meouche, Imane, Peltier, Johann, Monot, Marc, Soutourina, Olga, Pestel-Caron, Martine, Dupuy, Bruno, Pons, Jean-Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865298/
https://www.ncbi.nlm.nih.gov/pubmed/24358307
http://dx.doi.org/10.1371/journal.pone.0083748