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Mice Lacking NCF1 Exhibit Reduced Growth of Implanted Melanoma and Carcinoma Tumors

The NADPH oxidase 2 (NOX2) complex is a professional producer of reactive oxygen species (ROS) and is mainly expressed in phagocytes. While the activity of the NOX2 complex is essential for immunity against pathogens and protection against autoimmunity, its role in the development of malignant tumor...

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Detalles Bibliográficos
Autores principales: Kelkka, Tiina, Pizzolla, Angela, Laurila, Juha Petteri, Friman, Tomas, Gustafsson, Renata, Källberg, Eva, Olsson, Olof, Leanderson, Tomas, Rubin, Kristofer, Salmi, Marko, Jalkanen, Sirpa, Holmdahl, Rikard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865299/
https://www.ncbi.nlm.nih.gov/pubmed/24358335
http://dx.doi.org/10.1371/journal.pone.0084148