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Mice Lacking NCF1 Exhibit Reduced Growth of Implanted Melanoma and Carcinoma Tumors
The NADPH oxidase 2 (NOX2) complex is a professional producer of reactive oxygen species (ROS) and is mainly expressed in phagocytes. While the activity of the NOX2 complex is essential for immunity against pathogens and protection against autoimmunity, its role in the development of malignant tumor...
Autores principales: | Kelkka, Tiina, Pizzolla, Angela, Laurila, Juha Petteri, Friman, Tomas, Gustafsson, Renata, Källberg, Eva, Olsson, Olof, Leanderson, Tomas, Rubin, Kristofer, Salmi, Marko, Jalkanen, Sirpa, Holmdahl, Rikard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865299/ https://www.ncbi.nlm.nih.gov/pubmed/24358335 http://dx.doi.org/10.1371/journal.pone.0084148 |
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