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Rho Associated Coiled-Coil Kinase-1 Regulates Collagen-Induced Phosphatidylserine Exposure in Platelets

BACKGROUND: The transbilayer movement of phosphatidylserine mediates the platelet procoagulant activity during collagen stimulation. The Rho-associated coiled-coil kinase (ROCK) inhibitor Y-27632 inhibits senescence induced but not activation induced phosphatidylserine exposure. To investigate furth...

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Detalles Bibliográficos
Autores principales: Dasgupta, Swapan K., Le, Anhquyen, Haudek, Sandra B., Entman, Mark L., Rumbaut, Rolando E., Thiagarajan, Perumal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865301/
https://www.ncbi.nlm.nih.gov/pubmed/24358370
http://dx.doi.org/10.1371/journal.pone.0084649