Notch γ-Secretase Inhibitor Dibenzazepine Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm in ApoE Knockout Mice by Multiple Mechanisms

Abdominal aortic aneurysm (AAA) is a life-threatening aortic disease in the elderly. Activation of Notch1 pathway plays a critical role in the development of AAA, but the underlying mechanisms remain poorly understood. In the present study, we explored the mechanisms by which Notch1 activation regul...

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Detalles Bibliográficos
Autores principales: Zheng, Yue-Hong, Li, Fang-Da, Tian, Cui, Ren, Hua-Liang, Du, Jie, Li, Hui-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865307/
https://www.ncbi.nlm.nih.gov/pubmed/24358274
http://dx.doi.org/10.1371/journal.pone.0083310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865307/
https://www.ncbi.nlm.nih.gov/pubmed/24358274
http://dx.doi.org/10.1371/journal.pone.0083310

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