A p53 Drug Response Signature Identifies Prognostic Genes in High-Risk Neuroblastoma

Chemotherapy induces apoptosis and tumor regression primarily through activation of p53-mediated transcription. Neuroblastoma is a p53 wild type malignancy at diagnosis and repression of p53 signaling plays an important role in its pathogenesis. Recently developed small molecule inhibitors of the MD...

Descripción completa

Detalles Bibliográficos
Autores principales: Barbieri, Eveline, De Preter, Katleen, Capasso, Mario, Johansson, Peter, Man, Tsz-Kwong, Chen, Zaowen, Stowers, Paris, Tonini, Gian Paolo, Speleman, Frank, Shohet, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865347/
https://www.ncbi.nlm.nih.gov/pubmed/24348903
http://dx.doi.org/10.1371/journal.pone.0079843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865347/
https://www.ncbi.nlm.nih.gov/pubmed/24348903
http://dx.doi.org/10.1371/journal.pone.0079843

Ejemplares similares