A p53 Drug Response Signature Identifies Prognostic Genes in High-Risk Neuroblastoma

Chemotherapy induces apoptosis and tumor regression primarily through activation of p53-mediated transcription. Neuroblastoma is a p53 wild type malignancy at diagnosis and repression of p53 signaling plays an important role in its pathogenesis. Recently developed small molecule inhibitors of the MD...

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Detalles Bibliográficos
Autores principales: Barbieri, Eveline, De Preter, Katleen, Capasso, Mario, Johansson, Peter, Man, Tsz-Kwong, Chen, Zaowen, Stowers, Paris, Tonini, Gian Paolo, Speleman, Frank, Shohet, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865347/
https://www.ncbi.nlm.nih.gov/pubmed/24348903
http://dx.doi.org/10.1371/journal.pone.0079843

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