Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signals

Pre-B cell receptor (pre-BCR) signaling and migration from IL-7–rich environments cooperate to drive pre-B cell differentiation via transcriptional programs that remain unclear. We show that the Ikaros transcription factor is required for the differentiation of large pre-B to small pre-B cells. Mice...

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Detalles Bibliográficos
Autores principales: Heizmann, Beate, Kastner, Philippe, Chan, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865471/
https://www.ncbi.nlm.nih.gov/pubmed/24297995
http://dx.doi.org/10.1084/jem.20131735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865471/
https://www.ncbi.nlm.nih.gov/pubmed/24297995
http://dx.doi.org/10.1084/jem.20131735

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