Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A

Many solid cancers display cellular hierarchies with self-renewing, tumorigenic stemlike cells, or cancer-initiating cells (CICs) at the apex. Whereas CICs often exhibit relative resistance to conventional cancer therapies, they also receive critical maintenance cues from supportive stromal elements...

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Detalles Bibliográficos
Autores principales: Lotti, Fiorenza, Jarrar, Awad M., Pai, Rish K., Hitomi, Masahiro, Lathia, Justin, Mace, Adam, Gantt, Gerald A., Sukhdeo, Kumar, DeVecchio, Jennifer, Vasanji, Amit, Leahy, Patrick, Hjelmeland, Anita B., Kalady, Matthew F., Rich, Jeremy N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865474/
https://www.ncbi.nlm.nih.gov/pubmed/24323355
http://dx.doi.org/10.1084/jem.20131195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865474/
https://www.ncbi.nlm.nih.gov/pubmed/24323355
http://dx.doi.org/10.1084/jem.20131195

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