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Nfil3-independent lineage maintenance and antiviral response of natural killer cells

Development of the natural killer (NK) cell lineage is dependent on the transcription factor Nfil3 (or E4BP4), which is thought to act downstream of IL-15 signaling. Nfil3-deficient mice lack NK cells, whereas other lymphocyte lineages (B, T, and NKT cells) remain largely intact. We report the appea...

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Detalles Bibliográficos
Autores principales: Firth, Matthew A., Madera, Sharline, Beaulieu, Aimee M., Gasteiger, Georg, Castillo, Eliseo F., Schluns, Kimberly S., Kubo, Masato, Rothman, Paul B., Vivier, Eric, Sun, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865482/
https://www.ncbi.nlm.nih.gov/pubmed/24277151
http://dx.doi.org/10.1084/jem.20130417