A renin transcript lacking exon 1 encodes for a non-secretory intracellular renin that increases aldosterone production in transgenic rats

Renin transcripts lacking exon 1 and thus the signal sequence for co-translational transport to the endoplasmatic reticulum encode for a protein (exon[2-9]renin), that is confined to the cytoplasm. The function of exon(2-9)renin is currently unknown. Mitochondrial renin increases under conditions wh...

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Detalles Bibliográficos
Autores principales: Peters, Jörg, Wanka, Heike, Peters, Barbara, Hoffmann, Sigrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865667/
https://www.ncbi.nlm.nih.gov/pubmed/18782187
http://dx.doi.org/10.1111/j.1582-4934.2008.00132.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865667/
https://www.ncbi.nlm.nih.gov/pubmed/18782187
http://dx.doi.org/10.1111/j.1582-4934.2008.00132.x

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