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Inhibition of ERK attenuates autophagy and potentiates tumour necrosis factor-α-induced cell death in MCF-7 cells

The role of autophagy in cell death is under considerable debate. The process of autophagy has been shown to lead to either cell survival or cell death depending on cell type and stimulus. In the present study, we determined the contribution of ERK1/2 signalling to autophagy and cell death induced b...

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Detalles Bibliográficos
Autores principales: Sivaprasad, U, Basu, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865671/
https://www.ncbi.nlm.nih.gov/pubmed/18266953
http://dx.doi.org/10.1111/j.1582-4934.2008.00282.x