Bone morphogenic protein signalling suppresses differentiation of pluripotent cells by maintaining expression of E-Cadherin

Bone morphogenic protein (BMP) signalling contributes towards maintenance of pluripotency and favours mesodermal over neural fates upon differentiation, but the mechanisms by which BMP controls differentiation are not well understood. We report that BMP regulates differentiation by blocking downregu...

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Detalles Bibliográficos
Autores principales: Malaguti, Mattias, Nistor, Paul A, Blin, Guillaume, Pegg, Amy, Zhou, Xinzhi, Lowell, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865744/
https://www.ncbi.nlm.nih.gov/pubmed/24347544
http://dx.doi.org/10.7554/eLife.01197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865744/
https://www.ncbi.nlm.nih.gov/pubmed/24347544
http://dx.doi.org/10.7554/eLife.01197

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