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The auto-inhibitory domain and ATP-independent microtubule-binding region of Kinesin heavy chain are major functional domains for transport in the Drosophila germline

The major motor Kinesin-1 provides a key pathway for cell polarization through intracellular transport. Little is known about how Kinesin works in complex cellular surroundings. Several cargos associate with Kinesin via Kinesin light chain (KLC). However, KLC is not required for all Kinesin transpor...

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Detalles Bibliográficos
Autores principales: Williams, Lucy S., Ganguly, Sujoy, Loiseau, Philippe, Ng, Bing Fu, Palacios, Isabel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865757/
https://www.ncbi.nlm.nih.gov/pubmed/24257625
http://dx.doi.org/10.1242/dev.097592