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Network-based stratification of tumor mutations

Many forms of cancer have multiple subtypes with different causes and clinical outcomes. Somatic tumor genome sequences provide a rich new source of data for uncovering these subtypes but have proven difficult to compare, as two tumors rarely share the same mutations. Here we introduce network-based...

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Detalles Bibliográficos
Autores principales: Hofree, Matan, Shen, John P, Carter, Hannah, Gross, Andrew, Ideker, Trey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866081/
https://www.ncbi.nlm.nih.gov/pubmed/24037242
http://dx.doi.org/10.1038/nmeth.2651