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Polycomb Protein SCML2 Regulates the Cell Cycle by Binding and Modulating CDK/CYCLIN/p21 Complexes

Polycomb group (PcG) proteins are transcriptional repressors of genes involved in development and differentiation, and also maintain repression of key genes involved in the cell cycle, indirectly regulating cell proliferation. The human SCML2 gene, a mammalian homologue of the Drosophila PcG protein...

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Detalles Bibliográficos
Autores principales: Lecona, Emilio, Rojas, Luis Alejandro, Bonasio, Roberto, Johnston, Andrew, Fernández-Capetillo, Oscar, Reinberg, Danny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866099/
https://www.ncbi.nlm.nih.gov/pubmed/24358021
http://dx.doi.org/10.1371/journal.pbio.1001737