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Polycomb Protein SCML2 Regulates the Cell Cycle by Binding and Modulating CDK/CYCLIN/p21 Complexes
Polycomb group (PcG) proteins are transcriptional repressors of genes involved in development and differentiation, and also maintain repression of key genes involved in the cell cycle, indirectly regulating cell proliferation. The human SCML2 gene, a mammalian homologue of the Drosophila PcG protein...
Autores principales: | Lecona, Emilio, Rojas, Luis Alejandro, Bonasio, Roberto, Johnston, Andrew, Fernández-Capetillo, Oscar, Reinberg, Danny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866099/ https://www.ncbi.nlm.nih.gov/pubmed/24358021 http://dx.doi.org/10.1371/journal.pbio.1001737 |
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